Comparative studies of spermatogenesis in fertile and subfertile men.

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Comparative studies of spermatogenesis in fertile and subfertile men.

Testicular biopsy specimens from 16 fertile and 10 subfertile men with normal male karyotype were studied quantitatively to provide histological and cytogenetic data for a basis of reference in assessing abnormalities of spermatogenesis. Histological studies included estimation of the proportion and activity of germinal epithelium and an assessment of tubular morphology. In cytogenetic preparat...

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Apoptotic gene expression in potentially fertile and subfertile men.

Human sperm contain similar amounts of protamine-1 (P1) and protamine-2 (P2). Although an aberrant protamine ratio have been observed in subfertile men, functional evidence is provided by protamine knockout mice exhibiting male infertility. As sperm DNA integrity is known to be linked with DNA fragmentation and apoptosis, we investigated whether the DNA fragmentation factor 40 (DFF40) ratio or ...

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Vitrification induced apoptosis in spermatozoa from fertile and subfertile men

Background: Phospholipids are distributed asymmetrically between inner and outer leaflets of the plasma membrane of live cells. Early during apoptosis, this asymmetry is disrupted and phosphatidylserine becomes exposed on the outside surface of the plasma membrane. There is little information about the effects of vitrification on apoptosis. Objective: The aim of the present study was to evaluat...

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vitrification induced apoptosis in spermatozoa from fertile and subfertile men

background: phospholipids are distributed asymmetrically between inner and outer leaflets of the plasma membrane of live cells. early during apoptosis, this asymmetry is disrupted and phosphatidylserine becomes exposed on the outside surface of the plasma membrane. there is little information about the effects of vitrification on apoptosis. objective: the aim of the present study was to evaluat...

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Comparison of Sperm Parameters Between Fertile and Subfertile Couples

Purpose: In each society approximately 15% of couples suffer from fertility disorders and half of these are up to male factors. The aim of this study was to design and perform a prospective study to analyze and compare sperm parameters of feriite and sub fertile couples, in order to determine the minimum values required for fertility in Isfahan. Materials and Methods: 20o semen samples from pa...

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ژورنال

عنوان ژورنال: Journal of Clinical Pathology

سال: 1981

ISSN: 0021-9746

DOI: 10.1136/jcp.34.2.145